Repulsive Guidance Molecule b Deficiency Induces Gut Microbiota Dysbiosis and Increases the Susceptibility to Intestinal Inflammation in Mice

Imbalance of gut microbiota can induce or aggravate intestinal inflammation.To enhance our understanding of the molecular mechanisms of gut microbiota and inflammatory bowel disease (IBD), we studied the role of repulsive guidance molecule b (RGMb) in gut microbiota and colitis in mice.We generated Rgmb knockout mice and inducible Rgmb knockout mic

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APPROACHES TO SELECTION OF REVASCULARIZED CORTICO-PERIOSTAL AUTOTRANSPLANTS IN RECONSTRUCTIVE SURGERY OF THE EXTREMITIES

Aim of the study.Determination of characteristics of anatomical zones, which can be used for collection of revascularized cortico-periostal transplants.Materials and methods.Anatomy and haemodynamic characteristics of tissue complex, localised National Park Map in the areas, which can be used for the collection of revascularized cortico-periostal t

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Photosensitizers Mediated Photodynamic Inactivation against Fungi

Superficial and systemic fungal infections are essential problems for the modern health care system.One of the challenges is the growing resistance of fungi to classic antifungals and the constantly increasing cost of therapy.These factors force the scientific world to intensify National Park Map the search for alternative and more effective method

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